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The significance of the "free exercise clause" lies in its role in protecting an individual's right to practice their religion freely without government interference. This clause is part of the First Amendment of the United States Constitution and is crucial in ensuring that individuals can express and engage in their religious beliefs without facing discrimination or punishment by the state.

Essentially, the free exercise clause guarantees that individuals have the liberty to follow their religious convictions and engage in practices associated with their faith. This includes everything from attending religious services, following dietary restrictions, to observing religious holidays. The prominence of this clause is evident in numerous court cases where individuals have sought to assert their religious freedoms against laws or policies that they argue infringe upon their rights.

The other options, while related to the broader context of religion and government, do not accurately capture the essence of what the free exercise clause specifically addresses. For instance, the concept of preventing the establishment of a state religion relates more closely to the establishment clause, which functions to separate church and state rather than protect individual practice. The regulation of business practices in religious institutions is a more complex area that does not directly pertain to the free exercise of religion. Similarly, the idea of mandating a government role in religious activities conflicts with the principle of free